Researchers conducted the study for evaluating the prevalence of and factors associated with left ventricular diastolic dysfunction (LVDD) in youth with obesity and elevated blood pressure (BP). Cross-sectional analyses of baseline and follow up visits of 83 youth, 5-21 years, assessed for overweight/obesity and elevated BP in a multidisciplinary clinic. Using pediatric criteria, LVDD was present in a substantial proportion of youth with overweight/obesity and elevated BP. Those with LVDD had significantly greater measures of adiposity and BP vs those without LVDD and DBP z-score was an independent predictor of LVDD by E/A. Such data highlight the significance of preventing and treating CVD risk factors in childhood.